Publications

Discovery
A. Bashir, Q. Yang, J. Wang, S. Hoyer, W. Chou, C. McLean, G. Davis, Q. Gong, Z. Armstrong, J. Jang, H. Kang, A. Pawlosky, A. Scott, G. E. Dahl, M. Berndl, M. Dimon, B. S. Ferguson

Machine learning guided aptamer refinement and discovery

J. Wang, J. Yu, Q. Yang, J. McDermott, A. Scott, M. Vukovich, R. Lagrois, Q. Gong, W. Greenleaf, M. Eisenstein, B. S. Ferguson, H. T. Soh

Multi-Parameter Particle Display (MPPD): A Quantitative Screening Method for Discovery of Highly Specific Aptamers

H. Qu, A.T. Csordas, J. Wang, S-S Oh, M. Eisenstein, and H.T. Soh

Rapid and label-free strategy to select aptamers for metal ions

J. Wang, Q. Gong, N. Maheshwari, M. Eisenstein, M.L. Arcila, K.S. Kosik, H.T. Soh

Particle Display: A Quantitative Screening Method for Generating High-Affinity Aptamers

Q. Gong, J. Wang, K. M. Ahmad, A. T. Csordas, J. Zhou, J. Nie, R. Stewart, J. Thomson, J. Rossi, and H. T. Soh

Selection Strategy to Generate Aptamer Pairs that Bind to Distinct Sites on Protein Target

J. Wang, Y. Liu, T. Teesalu, K.N. Sugahara, V.R. Kotamraju, J.D. Adams, B.S. Ferguson, Q.Gong, S.S. Oh, A.T. Csordas, M. Cho, E. Ruoslahti, Y. Xiao, and H.T. Soh

Selection of Phage-Displayed Peptides on Live Adherent Cells in Microfluidic Channels

X. Lou, J. Qian, Y. Xiao, L. Viel, A.E. Gerdon, E.T. Lagally, P. Atzberger, T.M. Tarasow, A.J. Heeger, and H.T. Soh

Micromagnetic Selection of Aptamers in Microfluidic Channels

A. Csordas, A. Jorgensen, J. Wang, E. Gruber, Q. Gong, E. Bagley, M. Nakamoto, M. Eisenstein, and H.T. Soh

High-throughput discovery of aptamers for sandwich assays

S. Meyer, J.P. Maufort, J. Nie, R. Stewart, B. McIntosh, L. Conti, K.M. Ahmad, H.T. Soh and J.A. Thomson

Development of an Efficient Targeted Cell-SELEX Procedure for DNA Aptamer Reagents

M. Cho, S.S. Oh, J. Nie, R. Stewart, M.S. Eisenstein, J. Chambers, J.D. Marth, F. Walker, J.A. Thomson, H.T. Soh

Quantitative Selection and Parallel Characterization of Aptamers

K. Ahmad, Y. Xiao and H.T. Soh

Selection is More Intelligent than Design: Improving the Affinity of a Bivalent Ligand through Directed Evolution

J. Wang, J.F. Rudzinski, Q. Gong, H. T. Soh, P.J. Atzberger

Influence of Target Concentration and Background Binding on In Vitro Selection of Affinity Reagents,

M. Cho, Y. Xiao, J. Nie, R. Stewart, A. Csordas, S. S. Oh, J. Thomson, H. T. Soh

Quantitative Selection of DNA Aptamers through Microfluidic Selection and High Throughput Sequencing

Biosensing
P.L. Mage, B.S. Ferguson, D. Maliniak, K.L Ploense, T.E. Kippin and H.T. Soh

Closed-loop control of circulating drug levels in live animals

B.S. Ferguson, D.A. Hoggarth, D. Maliniak, K. Ploense, R.J. White, N. Woodward, K. Hsieh, A.J. Bonham, M. Eisenstein, T. Kippin, K.W. Plaxco and H.T. Soh

Real-time, aptamer-based tracking of circulating therapeutic agents in living animals

S.S. Oh, K. Plaxco, Y. Xiao, M. Eisenstein, and H.T. Soh

In Vitro Selection of Shape-Changing DNA Nanostructures Capable of Binding-Induced Cargo Release

I. Olmsted, Y. Xiao, M. Cho, A. Csordas, J. Sheehan, J. Meiler, H. T. Soh, and D. Bornhop

Measurement of Aptamer-Protein Interactions with Back-Scattering Interferometry

B.S. Ferguson, S.F. Buchsbaum, T.T. Wu, K. Hsieh, Y. Xiao, R. Sun and H.T. Soh

Genetic Analysis of H1N1 Influenza Virus from Throat Swab Samples in a Microfluidic System for Point-of-Care Diagnostics

A. Csordas, A.E. Gerdon, J.D. Adams, J. Qian, S.S. Oh, Y. Xiao, and H.T. Soh

Detection of Proteins in Serum via Micromagnetic Aptamer PCR (MAP) Technology

B.S. Ferguson, S. Buchsbaum, J. Swensen, K. Hsieh, X.H. Lou, and H.T. Soh

Integrated Microfluidic Electrochemical DNA Sensor

J. Swensen, Y. Xiao, B.S. Ferguson, A. Lubin, R. Lai, A.J Heeger, K.W. Plaxco, and H.T. Soh

Continuous Real-Time Monitoring of Cocaine in Undiluted Blood Serum via a Microfluidic Electrochemical Aptamer-Based Sensor